Cochrane continues to seek stable funding

Cochrane Canada to lose primary funding.

Startups That Seek to “Disrupt” Get More Funding Than Those That Seek to “Build”

Editorial: Stable funding for open source software?

Oliver Goldsmith said, ‘Where wealth accumulates, men decay’: this should make many programmers of free open source software some of the healthiest people on the planet. One can only aspire to be of independent means and become what the Victorians might have called ‘A gentleman bioinformatician’; after all, if you’re going to have delusions you may as well have really satisfying ones. The reali...

p53 continues to surprise

As one of the most intensively studied transcription factors, it is unsurprising that p53 is involved in many biological processes, including cell cycle arrest, DNA repair, senescence and apoptosis.1 its activities are mainly regulated by posttranslational modifications and interactions with other cellular components. Over the past few years, p53 has also been linked to redox homeostasis, the b...

Evidence Continues to Mount

In recent years, numerous groups of investigators have reported primary aldosteronism (PAL) to be much more common than previously thought.1–4 This has followed recognition of the aldosterone/renin ratio (ARR) as an improved, more sensitive method of screening for PAL and the application of ARR testing to a wider population, to include normokalemic, as well as hypokalemic, hypertensive subjects...